2nd WORKSHOP ON ENDOTHELIUM - FROM PHYSIOLOGY TO DISEASE MECHANISMS

We welcome you to the

Second Spanish Workshop on Endothelium

to be held in Santiago de Compostela on the 9^th of June 2023, in the Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), in the University of Santiago. The workshop will take place on a single day, as seen in the downloadable program. Different aspects of the endothelium will be covered, from fundamental biology to inflammation and pathophysiology. We believe it will be a very fruitul and useful meeting, with lots of lively discussions and network building. Our speakers will be:

Ellie Tzima. University of Oxford Medical Science Division.
Andreas Fischer. University Medical Center, Goettingen University.
Claudio A. Franco. Instituto de Medicina Molecular Joao Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa.
Jaime Millán. Centro de Biología Molecular Severo Ochoa
Mariona Graupera. Josep Carreras Leukaemia Research Institute.
Rui Benedito. Centro Nacional de Investigaciones Cardiovasculares.
Carmen Marín. Universidad de León.
Alicia García Arroyo. Centro de Investigaciones Biológicas.
María Jesús Sanz. Universitat de Valencia.
Luisa Botella. Centro de Investigaciones Biológicas.
Juan Zalvide. CiMUS. Universidade de Santiago de Compostela.
Eduardo Oliver. Centro de Investigaciones Biológicas.
Melissa García Caballero. Universidad de Málaga.
Natalia Reglero. Centro de Biología Molecular Severo Ochoa
Sandra D Castillo. Josep Carreras Leukaemia Institute

IMPORTANT DATES

Abstract submission: 1^st February to 30^th April 2023

Registration: 3^rd April to 26^th May 2023

ORGANIZING COMMITTEE

Dr. Ezequiel Álvarez (IDIS)
Dr. Manuel Campos Toimil (CiMUS-USC)
Dr. Francisco Campos (IDIS)
Dra. Natalia Reglero (CBM-CSIC-UAM)
Dra. Celia Pombo (CiMUS-USC)
Dr. Juan Zalvide (CiMUS-USC)

OUTLINE

The workshop will be held on June 9th, in the Centro de Investigación de Medicina Molecular y Enfermedades Crónicas (CIMUS), Avenida de Barcelona s/n, Campus Vida, Santiago de Compostela. In principle, the activities will be:

Workshop dinner: June 8th.

Workshop: June 9th.

Plenary speakers
- Ellie Tzima. University of Oxford Medical Science Division.
- Andreas Fischer. University Medical Center, Goettingen University.
Speakers
- Jaime Millán. Centro de Biología Molecular Severo Ochoa
- Mariona Graupera. Josep Carreras Leukaemia Research Institute.
- Rui Benedito. Centro Nacional de Investigaciones Cardiovasculares.
- Alicia García Arroyo. Centro de Investigaciones Biológicas.
- María Jesús Sanz. Universitat de Valencia.
- Luisa Botella. Centro de Investigaciones Biológicas.
- Carmen Marín. Universidad de León.
- Claudio A. Franco. Instituto de Medicina Molecular Joao Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa.
- Juan Zalvide. CiMUS. Universidade de Santiago de Compostela.
- Eduardo Oliver. Centro de Investigaciones Biológicas.
- Melissa García Caballero. Universidad de Málaga.
- Natalia Reglero. CBM-CSIC-UAM
- Sandra D Castillo. Josep Carreras Leukaemia Institute

Program

SHORT AGENDA (draft)

Organizers: University of Santiago de Compostela (USC), Institute for Health research of Santiago de Compostela (IDIS)

Place: Research Center for Molecular Medicine and Chronic Diseases (CIMUS-USC), 15706, Santiago de Compostela

Date: June 9th, 2023

Workshop dinner, Thursday, June 8th, 2023

21:00 Workshop dinner

Workshop, Friday, June 9^th, 2023

08.30h	Registration
09.00h	Opening session
09.30h	Keynote session 1: Andreas Fischer. Chair: Juan Zalvide Notch signaling in the endothelium - impact on cancer progression
10.30h	Bflow and Lincbiotech presentation
11.00h	Coffee break
11.30h	Session 1: Chair: Melissa García, Sandra Castillo. Rui Benedito. Incongruence between single-cell transcriptomics, genetics and vascular pathophysiology Claudio A Franco. Stochastic cell biology in vascular morphogenesis Juan Zalvide. GCKIII proteins and cavernoma development Mariona Graupera. Endothelial cells taking control of systemic metabolism
13.30h	Lunch and poster session (CiMUS Hall)
15.00h	Session 2: junior PI session (15 min/each + discussion). Chair: Jaime Millán, Alicia García. Eduardo Oliver. The endothelium as a target for pulmonary vascular diseases Melissa García Caballero. Digging into the metabolic profile of the endothelium Natalia Reglero. Unmasking novel roles for autophagy pathways in endothelial cells Sandra D. Castillo. New genetic landscape of vascular malformations
16.00h	Session 3: Chair. Natalia Reglero, Eduardo Oliver. María Jesús Sanz. New immune players in primary hypercholesterolemia and atherosclerosis lesion formation Carmen Marín TP73 regulates endothelial cell junctions and vascular integrity via AMOT/YAP Jaime Millán. Functional heterogeneity of the RhoA subfamily of GTPases in human endothelial barriers Alicia García Arroyo. Blood flow and beyond in microvasculature remodeling
18:00h	Keynote session 2: Ellie Tzima. Chair: Natalia Reglero. Endothelial cells coping with mechanical stress
19:00h	Closing remarks

Registration

Registration will be open from 3^rd April to 26^th May 2023

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Bank Transfer (It is mandatory to send proof of payment to xestioneventos@usc.es)

Account Holder: Universidade de Santiago de Compostela
Bank name: Banco Santander Central Hispano
Bank Account:
CODIGO SWIFT: BSCHESMM
IBAN: ES40 0049 2584 9022 1400 2210
Bank Address: Calderería, 54-56 - 15703 Santiago de Compostela
Concept to indicate: WORKSHOP ENDOTHELIUM - ASSISTANT NAME

Summary

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Total: €

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